Peer-reviewed veterinary case report
Dog with brain tumor invading nose and spreading to organs
By Takahashi, Tomoko et al.·Published in The Journal of veterinary medical science·2023·Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Anaplastic oligodendroglioma with nasal invasion and systemic metastasis in a dog.
- Species:
- dog
Plain-English summary
An 11-year-old spayed female French bulldog was brought in because she was suspected to have a nasal tumor. After imaging and tests, she was diagnosed with an aggressive brain tumor that had spread to her nasal cavity and possibly her lymph nodes. The vet treated her with radiation therapy, which helped her nasal congestion improve. Unfortunately, a few months later, new masses were found in her liver and spleen, and treatments with chemotherapy did not help. Sadly, she passed away about five months after her initial diagnosis.
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Abstract
An 11-year-old spayed female French bulldog was referred on suspicion of nasal tumor. Anaplastic oligodendroglioma in the olfactory bulb that was suspected to have invaded the nasal cavity was diagnosed from imaging and histopathology. Metastasis to cervical lymph nodes was suspected, with no other metastases identified. The brain-to-nasal lesion and lymph nodes were treated with hypo-fractionated radiation therapy. Nasal congestion soon resolved. About 3 months later, follow-up computed tomography revealed multiple hepatic and splenic masses, which were cytologically suspected as metastatic oligodendroglioma. Nimustine, followed by toceranib phosphate, seemed to have no effect, and the dog died on day 167. Postmortem examination revealed the primary tumor disappearance and systemic metastases. Canine oligodendroglioma can grow outside the cranial vault, and systemically metastasize.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37558495/