Peer-reviewed veterinary case report
Androgen insensitivity syndrome in a thoroughbred mare (64, XY--testicular feminization).
- Journal:
- The Canadian veterinary journal = La revue veterinaire canadienne
- Year:
- 2004
- Authors:
- Howden, Krista J
- Affiliation:
- Edmonton Equine Veterinary Services Inc.
- Species:
- horse
Plain-English summary
A Thoroughbred mare was brought in because she was acting like a stallion. After a thorough check-up that included looking at her reproductive system, ultrasounds, hormone tests, and genetic testing, she was diagnosed with androgen insensitivity syndrome, which means her body doesn't respond to male hormones properly. The veterinarians performed surgery to remove her abdominal testicles, and this successfully resolved her unusual behavior.
Abstract
A Thoroughbred mare was presented for stallion-like behavior. Reproductive and ultrasonographic evaluation, testosterone assays, and karyotyping confirmed a diagnosis of androgen insensitivity syndrome (64, XY--testicular feminization). Surgery to remove abdominal testicles was successful in alleviating the behavioral abnormality. This condition is discussed with reference to the current literature.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15283519/