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Peer-reviewed veterinary case report

Animal models for autoimmune bullous dermatoses.

Journal:
Experimental dermatology
Year:
2010
Authors:
Bieber, Katja et al.
Affiliation:
Institute of Anatomy · Germany

Abstract

Autoimmune bullous dermatoses are a group of severe diseases, which are clinically characterized by blisters and erosions of skin and/or mucous membranes. In order to investigate the pathogenesis of these potentially life-threatening diseases and to develop more specific therapeutic approaches, animal models have been developed that aim to reproduce the clinical, histological and immunopathological findings. We here review established and novel animal models of autoimmune skin blistering diseases and discuss their applications and limitations.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19702839/