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Peer-reviewed veterinary case report

Animal models for microbicide studies.

Journal:
Current HIV research
Year:
2012
Authors:
Veazey, Ronald S et al.
Affiliation:
Tulane University School of Medicine · United States

Abstract

There have been encouraging recent successes in the development of safe and effective topical microbicides to prevent vaginal or rectal HIV-1 transmission, based on the use of anti-retroviral drugs. However, much work remains to be accomplished before a microbicide becomes a standard element of prevention science strategies. Animal models should continue to play an important role in pre-clinical testing, with emphasis on safety, pharmacokinetic and efficacy testing.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22264049/