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Peer-reviewed veterinary case report

Animal models in oral cancer research.

Journal:
Oral oncology
Year:
2006
Authors:
Mognetti, B et al.
Affiliation:
Department of Biological and Clinical Science · Italy

Abstract

Biologically and clinically relevant animal models are essential in investigation of the progression of diseases and the elaboration of diagnostic or therapeutic protocols. The several rodent models used for in vivo evaluation for oral cancer employ chemical, transplantation and genetic (knockout and transgenic) induction methods. These models are described together with their advantages and disadvantages. Their optimization and application in future research may improve the early detection and treatment of oral cancer.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16266822/