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Peer-reviewed veterinary case report

Animal Models of Parkinson’s Disease: Are They Useful or Not?

Journal:
Journal of Parkinson's Disease
Year:
2020
Authors:
Barker, Roger A. & Björklund, Anders
Affiliation:
Department of Clinical Neuroscience and WT-MRC Cambridge Stem Cell Institute, Forvie Site, Cambridge, UK · United Kingdom

Abstract

The use of animal models in Parkinson’s disease research has been controversial in terms of how well they relate to the clinical condition and thus their utility for translating therapies from the lab to the clinic. In this article, two researchers debate this issue with Roger Barker taking the view that such models are not useful and may even be misleading, while Anders Björklund defends their use and highlights their value in better understanding and treating this condition.

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Original publication: https://doi.org/10.3233/jpd-202200