Peer-reviewed veterinary case report
Animal models of sepsis.
- Journal:
- Critical care clinics
- Year:
- 2009
- Authors:
- Zanotti-Cavazzoni, Sergio L & Goldfarb, Roy D
- Affiliation:
- Cooper University Hospital · United States
Abstract
In this review, we start with a general discussion of relevant factors that can determine the validity of a sepsis animal model. We briefly review some of the currently used animal models of sepsis (small animal models and large animal models). We discuss the clinical relevance of animal models in sepsis research today and address potential reasons for the apparent underperformance of animal models in predicting therapeutic success of novel drugs in clinical trials.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19892248/