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Peer-reviewed veterinary case report

Animal models of wound healing: utility in transgenic mice.

Journal:
Journal of biomaterials science. Polymer edition
Year:
2008
Authors:
Fang, Robert C & Mustoe, Thomas A
Affiliation:
Department of Surgery · United States
Species:
rodent

Abstract

Transgenic and knockout mouse technology represents a powerful tool for exploring the molecular pathways behind the wound healing process. The design and utilization of mouse wound healing models must be approached mindful of limitations of both the transgenic technology and the models themselves in order to continue generating useful information from studies with transgenic mice. A battery of standard and impaired wound healing models, when used in a systematic and combinatorial fashion, should yield significant contributions to wound healing research.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18644226/