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Peer-reviewed veterinary case report

Anti-diabetic effect of S-adenosylmethionine and α-glycerophosphocholine in KK-Amice.

Journal:
Bioscience, biotechnology, and biochemistry
Year:
2019
Authors:
Izu, Hanae et al.
Affiliation:
National Research Institute of Brewing · Japan

Abstract

Six-week-old male KK-Amice received drinking water with S-adenosylmethionine (SAM), α-glycerophosphocholine (GPC), or SAM+GPC for 10 weeks. The serum glucose of SAM+GPC at 15 weeks old, total cholesterol of GPC at 12 weeks old, and triglyceride of GPC at 15 weeks old and of SAM at 16 weeks old were reduced. SAM+GPC reduced serum leptin and food intake. Abbreviations: SAM: S-adenosylmethionine; GPC: α-glycerophosphocholine.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/30582404/