Peer-reviewed veterinary case report
Anti-hypoxia activity and related components of Rhodobryum giganteum par.
- Journal:
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Year:
- 2011
- Authors:
- Cai, Ying et al.
- Affiliation:
- General Hospital of Nanjing Military Area Command of Chinese PLA · China
- Species:
- rodent
Abstract
Different extracts of Rhodobryum giganteum Par. were screened with mice model of acute myocardial hypoxia induced by isoproterenol and pituitrin, eight compounds, i.e. p-hydroxycinnamic acid, caffeic acid-4-O-β-d-glucopyranoside, salicin, 7,8-dihydroxy coumarin, menthol, allantoin, palmitic acid, palmitamide were isolated and identified from the active fraction, among which p-hydroxycinnamic acid and 7,8-dihydroxy coumarin were confirmed having protective effects on myocardial hypoxia-reoxygenation injury, suggesting that these two components were major active ingredients of R. giganteum for cardiovascular disease.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20724127/