Peer-reviewed veterinary case report
Antibacterial effects of canine platelet-rich plasma and blood
By Attili, Anna-Rita et al.·Published in Frontiers in veterinary science·2021·School of Biosciences and Veterinary Medicine, Italy·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Antibacterial Properties of Canine Platelet-Rich Plasma and Other Non-Transfusional Hemo-Components: AnStudy.
- Species:
- dog
Plain-English summary
A study found that certain components from dog blood, like platelet-rich plasma and platelet gel, can help fight bacterial infections in dogs. These components were tested against various bacteria found in dog wounds, including some that are resistant to multiple antibiotics. The results showed that these blood products had a strong antibacterial effect, especially against tough Gram-negative bacteria. While the presence of white blood cells or platelets wasn't necessary for this effect, these findings suggest that using these blood components could be a helpful natural option for treating infections in dogs.
People also search for: dog wound infection treatment · platelet-rich plasma for dogs · antibacterial properties of dog blood
Abstract
Thisstudy was carried out to evaluate the potential antibacterial properties of canine non-transfusional hemo-components. Therapeutic formulations commonly used for regenerative medicine purposes (platelet-rich plasma, platelet gel, platelet lysate, fibrin glue), considering both leukocyte-rich and leukocyte-poor formulations, but also platelet-poor plasma and activating substances (thrombin, calcium gluconate), were tested to detect elements with potential antimicrobial properties. The antibacterial effect was tested on different bacterial strains (subspeciessubspecies, andsubspecies) isolated from canine wounds and classified as susceptible, multidrug-, extensively, and pandrug-resistant bacteria toward a known panel of human and veterinary antibiotics. The evaluation was carried out by agar gel diffusion method (Kirby-Bauer) and micro-inhibition in broth using microplates and spectrophotometer reading. The study findings confirmed the hypothesized antibacterial properties of canine non-transfusional hemo-components. A more effective bacteriostatic effect was found against Gram-negative bacteria, drug-resistant too. The presence of leukocytes or platelets does not appear to be essential for the antibacterial effect. Further studies should be conducted to evaluate the exact mechanism of action of the antimicrobial activity. However, non-transfusional hemo-components could be a useful natural aid in controlling bacterial infections in dogs.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34671662/