Peer-reviewed veterinary case report
Rifampin and doxycycline clear Ehrlichia canis infection in dogs
By Schaefer, John J et al.·Published in Annals of the New York Academy of Sciences·2008·Department of Veterinary Preventive Medicine, United States·View original on PubMed →
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Original publication title: Antibiotic clearance of Ehrlichia canis from dogs infected by intravenous inoculation of carrier blood.
- Species:
- dog
Plain-English summary
A group of Beagles infected with Ehrlichia canis, which causes canine monocytic ehrlichiosis (CME), were treated with either rifampin or doxycycline after showing symptoms of the disease. Both antibiotics helped improve their blood health and relieved signs of illness. After treatment, tests showed that the infections were cleared from all dogs, indicating that rifampin is a good alternative treatment for this condition.
People also search for: dog ehrlichiosis treatment · Beagle blood infection · rifampin for dogs · doxycycline for canine diseases
Abstract
Ehrlichia canis is the etiologic agent of canine monocytic ehrlichiosis (CME) and is a useful model for zoonotic tick-borne pathogens, many of which infect dogs. The purpose of this study was to evaluate rifampin and doxycycline regimens for clearance of E. canis infections in addition to alleviation of CME. Beagles were infected with E. canis by intravenous inoculation with carrier blood and treated with either rifampin or doxycycline after the acute phase of CME. Improved hematological values demonstrated that both treatments effectively relieved signs of the disease. Peripheral blood from all dogs became PCR negative after antibiotic treatment, suggesting that these infections were eliminated and that rifampin is an effective alternative chemotherapeutic agent for treatment of CME.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19120226/