Peer-reviewed veterinary case report
Antibiotic resistance in eye Staphylococcus pseudintermedius from dogs
By Kang, Min-Hee et al.·Published in Journal of veterinary science·2014·Department of Veterinary Internal Medicine, South Korea·View original on PubMed →
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Original publication title: Antibiotic resistance and molecular characterization of ophthalmic Staphylococcus pseudintermedius isolates from dogs.
- Species:
- dog
Plain-English summary
A study found that many dogs with eye infections had a type of bacteria called Staphylococcus pseudintermedius that showed high levels of antibiotic resistance. Out of 50 samples tested, most were resistant to common antibiotics like tetracycline and penicillin, while they were more susceptible to amoxicillin/clavulanic acid and chloramphenicol. This means that treating eye infections in dogs may require careful selection of antibiotics to avoid ineffective treatments. Pet owners should consult their veterinarian about the best options for treating their dog's eye issues, especially if previous treatments haven't worked.
People also search for: dog eye infection treatment · antibiotic resistance in dogs · Staphylococcus pseudintermedius in dogs
Abstract
The prevalence, virulence potential, and antibiotic resistance of ophthalmic Staphylococcus pseudintermedius (SP) isolated from dogs were examined. Sixty-seven Staphylococcus species were isolated from ophthalmic samples and surveyed for species-specific sequences in the Staphylococcus intermedius group (SIG) nuclease gene (SInuc), exfoliative toxin gene for SIG (siet), and antibiotic resistance genes (blaZ and mecA). PCR-restriction fragment length polymorphism analysis of the pta gene was also performed. Fifty isolates were identified as SIG strains, all of which were found to be SP. The blaZ gene was detected in 42 of the 50 SP strains and mecA gene was observed in 18 of the 50 SP strains. The 50 SP strains were most susceptible to amoxicillin/clavulanic acid (94%) and chlorampenicol (70%), and highly resistant to tetracycline (94%) and penicillin (92%). It was also found that 16 (88.9%) mecA-positive SP strains were resistant to oxacillin, tetracycline and penicillin. All mecA-positive SP were resistant to more than four of the eight tested antibiotics and therefore considered SP with multi-drug resistance (MDR). Our results indicate a high prevalence of antibiotic resistance genes in ophthalmic SP along with a close relationship between MDR SP strains and the mecA gene. Based on our findings, judicious administration of antibiotics to companion dogs is necessary.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24690601/