Peer-reviewed veterinary case report
Antibiotic resistance in dog deep skin infections from Streptococcus
By Imanishi, Ichiro et al.·Published in BMC veterinary research·2022·Department of Microbiology, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Antibiotic-resistant status and pathogenic clonal complex of canine Streptococcus canis-associated deep pyoderma.
- Species:
- dog
Plain-English summary
A group of older dogs with deep skin infections caused by Streptococcus canis were studied to understand the bacteria's resistance to antibiotics. Many of these dogs, particularly those over 10 years old, had strains that were resistant to multiple types of antibiotics, but most strains were still sensitive to penicillins. Veterinarians often used quinolones, but a significant number of the bacteria were resistant to this class. Fortunately, the study found that using penicillins combined with a beta-lactamase inhibitor was effective in treating these infections.
People also search for: dog skin infection treatment · antibiotic-resistant bacteria in dogs · deep pyoderma in older dogs · penicillin for dog infections
Abstract
BACKGROUND: Streptococcus canis causes deep pyoderma in canines, which raises concerns about the risk of isolates from lesions acquiring an antibiotic-resistant phenotype. It is necessary to identify effective antibiotics and the characteristics of the pathogenic cluster for S. canis-associated deep pyoderma. RESULTS: The signalment, molecular typing, and antibiotic-resistant status of S. canis isolated from deep pyoderma lesions (27 strains) and oral cavities (26 strains) were analyzed. Older dogs tended to have S. canis-associated deep pyoderma (15 of 27 dogs over 10 years old). Veterinarians chose quinolones for 10/16 cases (63%), even though the rate of quinolone-resistant strains of S. canis is 38-59%. Although 70% of the strains showed resistance to three or more antibiotic classes (37/53), 94% (50/53) strains showed sensitivity for penicillins. We also identified β-lactamase activity among penicillin-resistant strains of S. canis. Clonal complex 13 (CC13) was detected only in lesions and formed independent clusters in the phylogenetic tree. One strain of CC13 was resistant to the anti-methicillin-resistant Staphylococcus aureus drugs, vancomycin and linezolid. CONCLUSION: Although antibiotic-resistant strains of S. canis are isolated at a high rate, they can currently be treated with β-lactamase-inhibiting penicillins. CC13 may be a pathogenic cluster with high levels of antibiotics resistance.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36352470/