Peer-reviewed veterinary case report
Antibody levels in household dogs after combo vaccines with Leptospira
By Taguchi, M et al.·Published in The Veterinary record·2010·Taguchi Animal Hospital, Japan·View original on PubMed →
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Original publication title: Antibodies to parvovirus, distemper virus and adenovirus conferred to household dogs using commercial combination vaccines containing Leptospira bacterin.
- Species:
- dog
Plain-English summary
A group of household dogs were vaccinated with different commercial vaccines to see how well they protected against parvovirus, distemper, and adenovirus. The study found that vaccines containing Leptospira (a type of bacteria) led to higher antibody levels against parvovirus in two-year-old dogs and those over seven years old. While there were no significant differences in protection against distemper across age groups, some weight groups showed varying results. Overall, the findings suggest that including Leptospira in vaccines can enhance protection against certain viruses in dogs.
People also search for: dog parvovirus vaccine effectiveness · distemper vaccine for dogs · Leptospira in dog vaccines
Abstract
To examine how the inclusion (+) or exclusion (-) of inactivated Leptospira antigens in a vaccine for canine parvovirus type 2 (CPV-2), canine distemper virus (CDV) and canine adenovirus type 2 (CAdV-2) affects antibody titres to CPV-2, CDV and CAdV-1 antigens, household dogs were vaccinated with commercially available vaccines from one of three manufacturers. CPV-2, CDV and CAdV-1 antibody titres were measured 11 to 13 months later and compared within three different age groups and three different bodyweight groups. There were significant differences between CPV-2 antibody titres in dogs vaccinated with (+) vaccine and those vaccinated with (-) vaccine for two products in the two-year-old group and for one product in the greater than seven-year-old group; no significant differences were seen that could be attributed to bodyweight. No differences in CDV antibody titres were observed within age groups, but a significant difference was seen in the 11 to 20 kg weight group for one product. Significant differences in CAdV-1 antibody titres were seen for one product in both the two-year-old group and the ≤10 kg weight group.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21262693/