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Peer-reviewed veterinary case report

Antibody level comparison after porcine epidemic diarrhea vaccination via different immunization routes.

Journal:
Polish journal of veterinary sciences
Year:
2024
Authors:
Hu, C et al.
Affiliation:
Pulike Biological Engineering Inc. · China

Abstract

Porcine epidemic diarrhea (PED) is a disease extremely harmful to pig health. Intramuscular and Houhai acupoint injections are the main immunization routes to prevent and control PED. This study aimed to evaluate the efficacy of these two routes in pregnant sows based on serum IgG, IgA, and neutralizing antibody levels. PED virus (PEDV) immunoprophylaxis with live-attenuated and inactivated vaccines was administered. The vaccinations for the intramuscular injections elevated IgG and neutralizing antibody levels more than Houhai acupoint injections at most timepoints after immunization. However, the anti-PEDV IgA antibodies induced by vaccination with the two immunization routes did not differ significantly. In conclusion, intramuscular injections are better than Houhai acupoint injections for PEDV vaccination of pregnant sows.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38511679/