Peer-reviewed veterinary case report
Anticoagulant rodenticide poisoning signs and treatment in 21 dogs
By Sheafor, S E & Couto, C G·Published in Journal of the American Animal Hospital Association·1999·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Anticoagulant rodenticide toxicity in 21 dogs.
- Species:
- dog
Plain-English summary
Twenty-one dogs were brought in after being exposed to anticoagulant rodenticide, which is a type of poison used to kill rodents. The dogs showed symptoms like difficulty breathing, extreme tiredness, coughing up blood, and pale gums. Tests revealed issues with their blood clotting and several had low red blood cell counts. Treatment involved giving vitamin K1, blood transfusions, and other supportive care. Most of the dogs, about 83%, recovered well after treatment.
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Abstract
Twenty-three episodes of anticoagulant rodenticide toxicity were found in 21 dogs during a retrospective study conducted at The Ohio State University Veterinary Teaching Hospital. Dyspnea (57%), lethargy (48%), coughing/hemoptysis (30%), and pallor (26%) were the most common presenting complaints. Prolonged activated clotting time (ACT), prolonged one-stage prothrombin time (OSPT), and prolonged activated partial thromboplastin time (APTT) were present in all dogs that had not received any prior therapy. Anemia (83%), thrombocytopenia (61%), hypoproteinemia (57%), positive fibrin degradation products (FDPs) (55%, six of 11 tested), and hyperfibrinogenemia (43%, six of 14 tested) were common hematological findings. Treatment included therapy with vitamin K1, blood products, and supportive care. The survival rate was 83%.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9934927/