Peer-reviewed veterinary case report
Antidiuretic hormone-V2-receptor-aquaporin-2 system in rat kidneys during acute inflammation.
- Journal:
- Bulletin of experimental biology and medicine
- Year:
- 2004
- Authors:
- Misharin, A V et al.
- Affiliation:
- Research Center of Endocrinology
- Species:
- rodent
Abstract
Expression of antidiuretic hormone V(2)-receptor, water channel protein aquaporin-2, and cytokines interleukin-1b and interleukin-6 was studied in the kidneys of rats with acute inflammation produced by intraperitoneal injection of lipopolysaccharide in a dose of 250 microg/100 g. Reduced expression of aquaporin-2 and V(2)-receptor led to impairment of concentration capacity in the kidneys and decrease in urine osmolarity.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15723124/