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Peer-reviewed veterinary case report

Antiemetic efficacy of promethazine on xylazine-induced emesis in cats.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2012
Authors:
Kolahian, Saeed & Jarolmasjed, Seyed Hosein
Affiliation:
Department of Basic Sciences
Species:
cat

Abstract

The prophylactic antiemetic effect of 3 dosages of promethazine injected into cats 1 h before administration of xylazine was compared with that of a saline solution. Prior treatment with 2 and 4 mg/kg of promethazine significantly reduced the frequency of emetic episodes. Promethazine may be used as a prophylactic antiemetic in cats treated with xylazine.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22851784/