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Peer-reviewed veterinary case report

Antigen adsorbed calcium phosphate nanoparticles stimulate both innate and adaptive immune response in fish, Labeo rohita H.

Journal:
Cellular immunology
Year:
2011
Authors:
Behera, Truptimayee & Swain, Priyabrat
Affiliation:
Central Institute of Freshwater Aquaculture · India

Abstract

Calcium phosphate nanoparticles as an antigen/protein delivery was explored in a fish model Labeo rohita H. S-layer protein (of Aeromonas hydrophila) adsorbed on nano sized calcium phosphate particles elicited both innate and adaptive immune parameters which persisted up to 63 days of post immunization through parenteral immunization and gave cross protections.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21889128/