Peer-reviewed veterinary case report
Antiinflammatory and analgesic activities of Thesium chinense Turcz extracts and its major flavonoids, kaempferol and kaempferol-3-O-glucoside.
- Journal:
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- Year:
- 2007
- Authors:
- Parveen, Zahida et al.
- Affiliation:
- School of Life Sciences and Technology · China
Abstract
The ethyl acetate, chloroform extracts, and the two flavonoids kaempferol 1 and kaempferol-3-O-glucoside 2 isolated from whole plants of Thesium chinense Turcz were investigated for their antiinflammatory and analgesic activities. For the antiinflammatory activity, carrageenan-induced hind paw edema and xylene-induced mouse ear edema models, and for the analgesic activity, the acetic acid-induced abdominal constriction test was used. The ethyl acetate extract and two flavonoids showed significant (p<0.05 and p<0.01) and dose-dependent antiinflammatory and analgesic activity. The chloroform extract was inactive in the assay.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17666881/