Peer-reviewed veterinary case report
Cefovecin kills common skin and urinary bacteria in dogs and cats
By Stegemann, M R et al.·Published in Antimicrobial agents and chemotherapy·2006·Pfizer Animal Health, United Kingdom·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Antimicrobial activity and spectrum of cefovecin, a new extended- spectrum cephalosporin, against pathogens collected from dogs and cats in Europe and North America.
Plain-English summary
Cefovecin is a new antibiotic that can effectively treat bacterial infections in dogs and cats. It has been shown to kill a wide range of bacteria that cause skin, urinary tract, and dental infections. In tests, it worked well against common bacteria like Staphylococcus intermedius and E. coli, making it a strong option for veterinarians when treating pets with these types of infections. This means that if your dog or cat has a bacterial infection, cefovecin could be a good treatment choice.
People also search for: dog skin infection treatment · cat urinary tract infection antibiotics · cefovecin for dogs and cats
Abstract
Cefovecin is a new extended-spectrum semisynthetic cephalosporin indicated for the treatment of bacterial infections in dogs and cats. This study evaluated the in vitro activity and spectrum of cefovecin against 2,641 recent clinical isolates (1,660 canine and 981 feline isolates) from Europe and the United States. MIC determinations against cefovecin and other reference antimicrobials were performed by broth microdilution methods recommended by the Clinical and Laboratory Standards Institute (CLSI, formerly NCCLS). Cefovecin demonstrated bactericidal activity against both gram-positive and gram-negative pathogens. Cefovecin exhibited in vitro activity against all major aerobic and anaerobic bacterial pathogens associated with skin, urinary tract, and periodontal infections in dogs and cats. The MIC90 values of cefovecin against Staphylococcus intermedius, Escherichia coli, and Pasteurella multocida were 0.25 microg/ml, 1.0 microg/ml, and 0.06 microg/ml, respectively. No significant differences were observed in terms of the activities of cefovecin against pathogens from different European countries and against pathogens of European and U.S. origin.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16801403/