Peer-reviewed veterinary case report
Antibiotic resistance in Staphylococcus intermedius from dog skin
By Ganiere, J-P et al.·Published in Journal of veterinary medicine. B, Infectious diseases and veterinary public health·2005·Ecole Nationale Vé, France·View original on PubMed →
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Original publication title: Antimicrobial drug susceptibility of Staphylococcus intermedius clinical isolates from canine pyoderma.
- Species:
- dog
Plain-English summary
A study found that many dogs with skin infections caused by Staphylococcus intermedius bacteria are resistant to common antibiotics. Out of 50 samples from dogs with pyoderma, about 62% were resistant to penicillin, and many also showed resistance to other antibiotics like sulphonamides and oxytetracycline. However, a combination of clavulanic acid and amoxicillin, along with some other antibiotics, remained effective against these bacteria. This means that if your dog has a skin infection, your vet might consider using these effective treatments instead of the more commonly resisted antibiotics.
People also search for: dog skin infection antibiotics · Staphylococcus intermedius treatment · resistant bacteria in dogs
Abstract
A total of 50 Staphylococcus intermedius strains isolated in France from canine pyodermas in 2002 were investigated for their susceptibility to various antimicrobial drugs. Antimicrobial susceptibility was assessed using a 2-fold serial dilution method in Mueller-Hinton agar, and the minimal inhibitory concentrations (MICs) were determined. About 62% of the 50 strains tested were producers of beta-lactamase and categorized as penicillin-resistant. About 26% demonstrated resistance to sulphonamides, 46% to oxytetracycline, 30% to chloramphenicol, 28% to streptomycin, kanamycin, neomycin or erythromycin, 22% to clindamycin, 6% to doxycycline, 2% to gentamicin, enrofloxacin, marbofloxacin or pradofloxacin. Acquired resistance was not observed to a clavulanic acid-amoxicillin combination, oxacillin, cephalosporins (cephalexin, ceftiofur and cefquinome), trimethoprim, a sulphamethoxazole-trimethoprim combination and florfenicol. About 42% were simultaneously resistant to three or more antimicrobial classes (multiresistance). All isolates with acquired resistance to erythromycin were also resistant to streptomycin and neomycin/kanamycin. About 22% of isolates exhibited cross-resistance between erythromycin and clindamycin and all clindamycin-resistant isolates also exhibited resistance to erythromycin. Resistance to penicillin, oxytetracycline and chloramphenicol was also positively associated with resistance to erythromycin and streptomycin.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15702997/