Peer-reviewed veterinary case report
Antibiotic resistance rose in bacteria from dog urine samples over 8
By Guzmán Ramos, P J et al.Ā·Published in The Journal of small animal practiceĀ·2021Ā·School of Veterinary MedicineĀ·View original on PubMed ā
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Original publication title: Antimicrobial resistance increased over an 8-year period in Enterobacteriaceae cultured from canine urine samples.
- Species:
- dog
Plain-English summary
A study found that over an 8-year period, dogs with urinary tract infections showed an increase in antibiotic resistance among bacteria found in their urine samples. Escherichia coli was the most common bacteria identified, and while the overall rate of positive urine cultures didn't change much, the resistance to antibiotics rose significantly from 5.2% to 35.6%. This means that some bacteria are becoming harder to treat with standard medications. Pet owners should be aware of this trend and discuss appropriate treatment options with their veterinarian, especially if their dog has recurring urinary issues.
People also search for: dog urinary tract infection treatment Ā· antibiotic resistance in dogs Ā· Escherichia coli in dog urine
Abstract
OBJECTIVES: The aims of the present study were to describe the prevalence of positive urinary bacterial culture in dogs, to identify the most commonly isolated microorganisms and to analyse changes in antimicrobial susceptibility patterns over time. MATERIAL AND METHODS: A retrospective case series was performed using culture and susceptibility results from canine urine samples collected between January 2010 and December 2017. The presence or absence of infection, identity of the bacterium with heaviest growth, and susceptibility profile were recorded for each sample. Trends in the frequency of positive culture and antimicrobial resistance were assessed by Poisson regression modelling. Prevalence rate ratio and 95% confidence interval were reported for resistance to each antimicrobial. RESULTS: A positive urine culture was documented in 771 (22.5%) of 3420 samples. Escherichia coli was the most commonly isolated microorganism. There was no significant increase in the frequency of positive bacterial culture over the study period (prevalence rate ratio 0.98; 95% confidence interval: 0.92 to 1.0). Overall, there was an increase in antimicrobial resistance within Enterobacteriaceae from 5.2 to 35.6%. The prevalence of multidrug-resistant bacteria varied from year to year throughout the study period. However, the Poisson regression model identified a significant increase in the frequency of multidrug-resistant Enterobacteriaceae over this period, averaging approximately 22% per year (prevalence rate ratio 1.22, 95% confidence interval: 1.06 to 1.42). CLINICAL SIGNIFICANCE: The significant increase in antimicrobial resistance observed in this study is concerning and may have implications for veterinary and public health. Appropriate measures, such as antibiotic stewardship programmes, should be implemented to address increasing antimicrobial resistance.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33460135/