Antimicrobial resistance profiles ofspp. andisolated from dogs and cats in Seoul, South Korea during 2021-2023.

Abstract

We investigated the antimicrobial resistance (AMR) rates and profiles ofspp. and() isolated from dogs and cats in Seoul, South Korea during 2021-2023. We analyzed AMR profiles ofspp. andisolated from 2,180 samples (1,859 canine and 321 feline) collected from 36 veterinary clinics in Seoul, South Korea, as part of the Korean Veterinary Antimicrobial Resistance Monitoring System (2021-2023). A total of 484spp. isolates and 158isolates were identified and used for AMR test.spp. isolates exhibited the highest resistance to penicillin in both dogs (85%) and cats (29.81%). Multidrug-resistant (MDR)spp. was more prevalent in dogs (65%) than in cats (14.42%), with threeisolates from dogs and aisolate from a cat showing resistance to eight antibiotic classes. Methicillin-resistant(MRSP) constituted 105 out of 284isolates (36.97%) in dogs and seven strains out of 14 (50%) in cats.isolates demonstrated the highest resistance to cefalexin in both dogs (61.72%) and cats (56.67%). The prevalence of MDRwas higher in dogs (37.5%) than in cats (26.67%). This study highlights the concerning prevalence of AMR in commensal or potentially opportunistic pathogens from companion animals, particularly in dogs. It is crucial to promote the prudent use of antimicrobials in companion animals and ensure the ongoing monitoring of trends in antimicrobial-resistant bacteria to mitigate the selection and spread of antibiotic-resistant bacteria between humans and companion animals.