Peer-reviewed veterinary case report
Antibiotic effectiveness for Pseudomonas ear infections in dogs
By Mekić, S et al.·Published in The Veterinary record·2011·Department of Microbiology and Infectious Diseases with Clinic·View original on PubMed →
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Original publication title: Antimicrobial susceptibility of Pseudomonas aeruginosa isolates from dogs with otitis externa.
- Species:
- dog
Plain-English summary
A group of dogs with ear infections caused by Pseudomonas aeruginosa were tested to see which antibiotics worked best. The study found that ceftazidime was the most effective treatment, successfully fighting off the infection in all tested strains. Ticarcillin/clavulanic acid and ciprofloxacin also showed good results, while many strains were resistant to enrofloxacin and gentamicin. This information can help veterinarians choose the right medication for dogs suffering from otitis externa.
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Abstract
Pseudomonas aeruginosa is a common cause of otitis externa in dogs, and treatment of these infections is becoming problematic because of the increasing number of multiresistant strains. The aim of the present study was to compare the in vitro activities of cefepime, ceftazidime, enrofloxacin, ciprofloxacin, gentamicin and ticarcillin/clavulanic acid against 104 strains of P aeruginosa isolated from dogs with otitis externa. Antimicrobial susceptibility and minimum inhibitory concentrations, in µg/ml, were evaluated by the E test (bioMérieux). The most active compound was ceftazidime, with 100 per cent efficiency. The majority of tested strains were susceptible to ticarcillin/clavulanic acid (89.4 per cent), followed by ciprofloxacin (88.5 per cent) and cefepime (60.6 per cent). The highest resistance was observed to enrofloxacin (51.9 per cent) and gentamicin (43.3 per cent). Large numbers of strains were intermediately susceptible to antibiotics registered for use in veterinary medicine in Croatia--enrofloxacin (47.1 per cent) and gentamicin (41.3 per cent).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21742683/