Peer-reviewed veterinary case report
Antiulcerogenic activity of ethanolic leaf extract of Lasianthera africana.
- Journal:
- African journal of traditional, complementary, and alternative medicines : AJTCAM
- Year:
- 2009
- Authors:
- Okokon, Jude E et al.
- Affiliation:
- Department of Pharmacology and Toxicology
- Species:
- rodent
Abstract
The effect of ethanolic leaf extract of Lasianthera africana on experimentally induced ulcer was studied in rats. The extract (1000 - 3000mg/kg) inhibited ethanol-induced, indomethacin - induced and reserpine -induced ulcer models in a dose dependent fashion. The various degrees of inhibitions were statistically significant (p<0.01). The effect of the extract was comparable to that of the standard drugs used. Thus, Lasianthera africana extract demonstrated a good antiulcer activity which supports the antiulcer effect of this plant in traditional medicine.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20209006/