Peer-reviewed veterinary case report
Itraconazole shows antiviral effects against type I feline
By Takano, Tomomi et al.·Published in Veterinary research·2019·School of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Antiviral activity of itraconazole against type I feline coronavirus infection.
- Species:
- cat
Plain-English summary
A study found that itraconazole, a medication typically used for treating fungal infections in cats, may also help fight against type I feline coronavirus, which causes a serious disease called feline infectious peritonitis (FIP). This research showed that itraconazole can inhibit the virus both before and after infection in cells. While this is promising, it's important for cat owners to consult their veterinarian about the potential use of itraconazole for this viral infection.
People also search for: cat coronavirus treatment · feline infectious peritonitis medication · itraconazole for cats · how to treat FIP in cats
Abstract
Feline coronaviruses (FCoVs) are the causative agents of severe systemic disease (feline infectious peritonitis: FIP) in domestic and wild cats. FCoVs have been classified into serotypes I and II. Type I FCoV is the dominant serotype (approximately 70-90%) worldwide. Therefore, it is necessary to provide antiviral agents for type I FCoV infection. In this study, we demonstrated that itraconazole (ICZ), practically used for fungal infections in cats, inhibits the type I FCoV infection. ICZ also exhibited antiviral effect in cells after viral infection, suggesting that ICZ could potentially be used as a therapeutic.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30658691/