Peer-reviewed veterinary case report
Dog with hindlimb pain and artery clots from muscle angiosarcoma
By Wray, J D et al.·Published in The Journal of small animal practice·2006·Centre for Small Animal Studies and Centre for Preventive Medicine·View original on PubMed →
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Original publication title: Aortic and iliac thrombosis associated with angiosarcoma of skeletal muscle in a dog.
- Species:
- dog
Plain-English summary
A 7-year-old neutered male greyhound was brought in because he was limping and in pain in his hind legs. The vet found dead tissue in his toes and skin, along with a firm swelling in his thigh. Tests showed that blood clots had formed in the main artery supplying his hind legs, leading to severe tissue damage. Unfortunately, due to the poor prognosis caused by an aggressive cancer called angiosarcoma, the dog was euthanized.
People also search for: greyhound hind leg pain · dog angiosarcoma symptoms · dog blood clot treatment
Abstract
A seven-year-old, neutered male greyhound was presented with a history of episodic shifting hindlimb lameness and pain. Ischaemic necrosis of areas of the hindlimb digits and skin and a firm swelling within the medial right thigh musculature were found on physical examination. Investigation demonstrated thrombosis of the terminal aorta and right external iliac artery with ischaemic necrosis of muscular and dermal tissue distal to the sites of thrombosis. The dog was euthanased due to poor prognosis. Necropsy findings were of a poorly differentiated invasive sarcoma of the skeletal muscle of the proximal right hindlimb, thrombosis of the aorta and right external iliac artery and secondary renal glomerulopathy. Immunohistochemistry of the neoplastic tissue indicated angiosarcoma based on expression of CD31 and factor VIII-related antigen. Thrombosis was considered likely to be due to systemic hypercoagulability because of the presence of altered flow characteristics and endothelial damage in the vascular tumour bed. Aortoiliac thrombosis, paraparesis and hindlimb ischaemia are unusual sequelae of angiosarcoma in the dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16674722/