Application and research progress in composite stem cell materials of pelvic floor reconstruction.

Abstract

As an important tool for the surgical treatment of pelvic floor dysfunction, the safety of mesh must be guaranteed. Although the short-term curative effect of most synthetic mesh is satisfactory, complications often occur due to its material. Planting stem cells on mesh through specific methods may resolve the problems of mesh with poor biocompatibility or an uncontrollable rate o degradation. Based on recent research, this paper summarizes the research progress of stem cells composited with common mesh materials, such as polypropylene, polylactic acid and acellular matrix.