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Peer-reviewed veterinary case report

Hemodialysis treatment and results in 29 cats with kidney failure

By Langston, C E et al.·Published in Journal of veterinary internal medicine·1997·School of Veterinary Medicine, United States·View original on PubMed

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Original publication title: Applications and outcome of hemodialysis in cats: a review of 29 cases.

Species:
cat

Plain-English summary

A group of 29 cats with severe kidney failure underwent hemodialysis (a treatment that filters waste from the blood) to see if it could help them recover. The cats had high levels of toxins in their blood, and after treatment, many showed significant improvement in their kidney function. About 60% of the cats with acute kidney failure were able to recover enough to stop needing dialysis, but some experienced complications during treatment. While hemodialysis can be effective for severe cases, it may not be suitable for cats with advanced chronic kidney disease due to potential complications.

People also search for: cat kidney failure treatment · hemodialysis for cats · acute kidney failure in cats · cat dialysis recovery · complications of cat dialysis

Abstract

Hemodialysis (HD) has been used in the management of renal failure in dogs, but its feasibility has not been reported for uremic cats. Therefore, we investigated the technical possibility, efficacy, and complications of intermittent HD in cats with severe uremia. A total of 160 HD treatments were performed on 29 cats with acute renal failure (ARF) (n = 15), chronic renal failure (CRF) (n = 6), or acute on CRF (n = 8) between November 1993 and June 1996. Hemodialysis treatments were performed with transcutaneous dialysis catheters using a bicarbonate-based delivery system, sodium modeling, and volumetric-controlled ultrafiltration. Presenting serum chemistries (mean +/- SD) for all cats were creatinine, 16.4 +/- 7.5 mg/dL; blood urea nitrogen (BUN), 229 +/- 87 mg/dL; phosphate, 15.4 +/- 5.4 mg/dL; potassium, 6.0 +/- 1.6 mEq/L; and HCO3-, 16.0 +/- 4.4 mEq/L. For intensive HD treatments, pre-HD versus post-HD creatinine changed from 10.3 +/- 4.4 to 1.6 +/- 0.9 mg/dL and BUN from 105 +/- 33 to 8 +/- 10 mg/dL. One or more adverse events occurred during 111 (69%) treatments. Dialysis-related events included hypotension, dialysis dysequilibrium, clotting, and bleeding. Nine of 15 (60%) cats with ARF and 1 cat with CRF recovered sufficiently to survive without ongoing need for HD. For the remaining cats, the proximate causes of death were dialysis related in 9 cats, uremia related in 6 cats, and iatrogenic or unknown in 4 cats. Hemodialysis is technically feasible and effectively controls the biochemical disturbances of uremic cats. It is especially valuable for the management of severe ARF, permitting recovery in a large number of cats refractory to conventional therapy. Technical complications and chronic debility, however, may limit its usefulness for cats with advanced CRF.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9470160/