Peer-reviewed veterinary case report
Appraisal of the extent of chronic allograft vasculopathy in animal models: proposition of a standardized micromorphometric method.
- Journal:
- Atherosclerosis
- Year:
- 2005
- Authors:
- Rousvoal, Géraldine et al.
- Affiliation:
- Department of Cardiothoracic Surgery · United States
Abstract
Arterial obstruction due to intimal myproliferation is an outcome used for investigating chronic allograft vasculopathy in animal models. Since harvested tissue may be distorted while processing, discrepancy may happen in the measure of the obstruction. We propose a standardized micromorphometric method for calculating the percentage of obstruction with eliminating the variability in the shape of the vessel cross-section. The mathematical adjustment avoids the overestimation of the percentage of obstruction and improves accuracy.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15998518/