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Peer-reviewed veterinary case report

Arachidonate metabolites in bronchoalveolar lavage fluid from horses with and without COPD.

Journal:
Equine veterinary journal
Year:
1992
Authors:
Watson, E D et al.
Affiliation:
Department of Clinical Studies
Species:
horse

Abstract

Arachidonate metabolites were measured in bronchoalveolar lavage fluid (BALF) from horses with (N = 4) and without (N = 7) chronic obstructive pulmonary disease (COPD). Prostaglandin (PG) D2, leukotriene (LT) B4 and LTC4 were present in highest concentrations in BALF from clinically normal horses. Concentrations of PGE2 and PGF were significantly higher in BALF from horses with COPD than in BALF from normal horses, but no differences were detected in thromboxane B2, 6-keto-PGF1 alpha, PGD2, LTB4 or LTC4.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/1396512/