as a screening tool to study virulence factors of.

Abstract

The invertebratehas increasingly and widely been used in the last few years to study complex host-microbe interactions.is one of the most pathogenic fungi causing life-threatening diseases in humans and animals.larvae has been proven as a reliable model for the analysis of pathogenesis and virulence factors, enable to screen a large number ofstrains. This review describes the different uses ofto studyand provides a comparison of the different protocols to trace fungal pathogenicity. The review also includes a summary of the diverse mutants tested in, and their respective contribution tovirulence. Previous investigations indicated thatshould be considered as an interesting tool even though a mammalian model may be required to complete and verify initial data.