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Peer-reviewed veterinary case report

Aspergillosis granuloma in the mediastinum of a non-immunocompromised horse.

Journal:
The Cornell veterinarian
Year:
1993
Authors:
Moore, B R et al.
Affiliation:
Department of Veterinary Clinical Sciences · United States
Species:
horse

Plain-English summary

A National Show Horse was found to have a growth in the chest area called a mediastinal granuloma, which is a lump that can cause problems. The horse showed signs of being unwell, including a fever, runny nose, and coughing. Tests using imaging and samples from the lungs helped identify a fungal infection caused by a type of mold called Aspergillus. The diagnosis was confirmed after examining the tissue from the lump after the horse passed away.

Abstract

A National Show Horse with a mediastinal granuloma was presented with clinical signs which included fever, nasal discharge and cough. The mediastinal mass was identified radiographically and ultrasonographically. A presumptive diagnosis of aspergillosis was made following isolation of Aspergillus spp. from both transtracheal aspirate and bronchoalveolar lavage fluid samples and agar gel immunodiffusion (AGID) identification of serum antibody to Aspergillus spp. The diagnosis was confirmed by histopathologic examination of the mediastinal mass obtained at necropsy examination.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/8467705/