Peer-reviewed veterinary case report
Aspergillus eye infection causing severe eye inflammation in two dogs
By Wooff, Penelope J et al.·Published in Veterinary ophthalmology·2018·Guardian Veterinary Centre, United States·View original on PubMed →
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Original publication title: Aspergillus spp. panophthalmitis with intralenticular invasion in dogs: report of two cases.
- Species:
- dog
Plain-English summary
A 6-year-old male Labrador and a 7-year-old female mixed breed dog were brought in for severe eye problems, including painful swelling and increased pressure in one eye. Both dogs tested positive for a fungal infection caused by Aspergillus, which can lead to serious eye issues. The Labrador's eye did not improve with treatment and was removed for comfort, while the mixed breed responded to aggressive medical therapy but sadly had to be euthanized due to kidney failure. These cases highlight the importance of testing for fungal infections in dogs with unexplained eye problems.
People also search for: dog eye problems · Aspergillus infection in dogs · dog glaucoma treatment · why is my dog’s eye swollen · dog kidney failure symptoms
Abstract
This case series describes the ocular, clinical and histologic manifestations of disseminated Aspergillosis in two dogs. Two dogs presented for severe unilateral panophthalmitis and secondary glaucoma with positive Aspergillus spp. titers. Case 1 showed no clinicopathologic systemic symptoms of fungal dissemination, however, case 2 was affected with acute renal failure. The affected eye of case 1 did not respond to medical therapy and was enucleated for comfort. The affected eye of case 2 responded to aggressive topical and systemic medical therapies, however, the patient was euthanized for acute renal failure. Globes were collected for histologic evaluation at the time of death. Histology of both revealed panophthalmitis with presence of significant intraocular hemorrhage, multifocal fungal granulomas, retinal and optic nerve changes consistent with secondary glaucoma, rupture of the anterior lens capsule, and fungal invasion and colonization of the intralenticular space. These cases represent a unique and devastating ocular manifestation of disseminated Aspergillosis. Cases presenting with uveitis and secondary glaucoma of unknown origin, especially with confirmed or suspected lens capsular rupture, should have serologic testing for this infectious agent.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27641998/