Peer-reviewed veterinary case report
Effectiveness of two 10% fipronil spot-ons for cat flea control
By Cadiergues, Marie-Christine et al.·Published in Journal of feline medicine and surgery·2011·Ecole Nationale Vé, France·View original on PubMed →
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Original publication title: Assay of two 10% (w/v) fipronil spot-on formulations against feline infestations with Ctenocephalides felis.
- Species:
- cat
Plain-English summary
Eight cats were tested to see how well a new fipronil-based spot-on treatment worked against fleas. After applying the treatment, the number of fleas on the cats dropped by over 98% within two days. The cats remained protected from new flea infestations for up to 58 days. This suggests that the fipronil spot-on is highly effective for treating and preventing flea problems in cats.
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Abstract
A new fipronil-based spot-on formulation was evaluated against experimental flea infestations in cats in two studies. In both studies, eight cats served as negative controls (groups 1 and 4); on day 0, eight cats were treated with a 10% w/v fipronil-based spot-on solution (Effipro Spot-on, 0.5ml per cat, groups 2 and 5) and eight cats served as positive controls (Frontline Spot-on, 0.5ml per cat, groups 3 and 6). Each cat was infested on day - 1 with 50 fleas (study 1) and weekly (day 7-day 56) with 100 fleas (study 2). Geometric mean flea counts obtained 48h after the treatment or each re-infestation were reduced by 99.0 and 98.3% in groups 2 and 3, respectively, on day 2, compared to the negative control group. Cats were protected from re-infestations with an efficacy >99% for 58 days in group 5 and for 37 days in group 6.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21354841/