Peer-reviewed veterinary case report
Assay validation and diagnostic applications of major acute-phase protein testing in companion animals.
- Journal:
- Clinics in laboratory medicine
- Year:
- 2011
- Authors:
- Kjelgaard-Hansen, Mads & Jacobsen, Stine
- Affiliation:
- Department of Small Animal Clinical Sciences
Plain-English summary
In recent years, veterinarians have been using tests for major acute-phase proteins (APPs), which are substances that can indicate health issues, more frequently in pets. This is due to better understanding and improved testing methods that are specific to different animal species. While most studies show that these tests are good at detecting inflammation, there is still a lot of potential for using them more regularly in veterinary practice. Overall, the research suggests that major APP testing could be a valuable tool for diagnosing health problems in pets, but it hasn't been fully utilized yet.
Abstract
The use of major acute-phase proteins (APPs) for assessment of health and disease in companion animals has increased within the last decade because of increased knowledge in the field and increased access to appropriate assay systems for detection of relevant APPs, which are highly species specific. Despite evidence being restricted almost solely to proven excellent overlap performance of these markers in detecting inflammatory activity, clinically relevant studies at higher evidence levels do exist. The available body of literature shows a clear, but seemingly untapped, potential for more extended routine clinical use of major APP testing in companion animal medicine.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21295722/