Peer-reviewed veterinary case report
Maropitant versus ondansetron for vomiting in dogs with parvovirus
By Sullivan, Lauren A et al.·Published in Journal of the American Animal Hospital Association·2018·From the College of Veterinary Medicine and Biomedical Sciences, United States·View original on PubMed →
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Original publication title: Assessing the Efficacy of Maropitant Versus Ondansetron in the Treatment of Dogs with Parvoviral Enteritis.
- Species:
- dog
Plain-English summary
A group of dogs with parvoviral enteritis (a serious intestinal infection) were treated with either maropitant or ondansetron to see which medication worked better to stop vomiting and help them recover. Both treatments were given alongside IV fluids and other supportive care. The results showed that both medications were equally effective, with no significant differences in how long the dogs stayed in the hospital or how quickly they stopped vomiting. Ultimately, both maropitant and ondansetron helped the dogs recover from this illness.
People also search for: dog parvovirus treatment · maropitant for dog vomiting · ondansetron for dogs with parvo
Abstract
Antiemetics are commonly prescribed during the treatment of canine parvoviral enteritis. This blinded, randomized prospective study compared the quality of clinical recovery and duration of hospitalization in canine parvoviral dogs receiving either maropitant (1 mg/kg [0.45 mg/lb] IV q 24 hr, n = 11) or ondansetron (0.5 mg/kg [0.23 mg/lb] IV q 8 hr, n = 11). All dogs were treated with IV fluids, cefoxitin, and enteral nutrition. Frequency of vomiting and pain scoring were recorded twice daily. Rescue analgesics and antiemetics were administered as dictated by specific pain and vomiting criteria. Clinical severity scoring, body weight, and caloric intake were monitored daily. When comparing dogs receiving maropitant versus ondansetron, respectively, there were no differences in duration of hospitalization (3.36 ± 0.56 versus 2.73 ± 0.38 days, P = .36), requirement of rescue antiemetic (3/11 versus 5/11 dogs, P = .66), duration of vomiting (5 versus 4 days, P = .65), or days to voluntary food intake (2 versus 1.5 days, P = 1.0). Results of this study suggest that maropitant and ondansetron are equally effective in controlling clinical signs associated with parvoviral enteritis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30272481/