Peer-reviewed veterinary case report
How fast Advantage Multi kills hookworms in dogs
By Lee, Alice C Y et al.·Published in Veterinary parasitology·2014·Department of Microbiology and Immunology, United States·View original on PubMed →
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Original publication title: Assessing the speed of kill of hookworms, Ancylostoma caninum, by Advantage Multi ® for Dogs using endoscopic methods.
- Species:
- dog
Plain-English summary
Four dogs, two 4-year-old females and two 7-year-old males, were treated for hookworm infections caused by Ancylostoma caninum. After being infected, they received a topical treatment called Advantage Multi for Dogs. Endoscopic examinations showed that the hookworms were mostly gone within 24 hours of treatment, and the damage to their intestines improved significantly. This study suggests that Advantage Multi is effective at quickly eliminating hookworms and reducing related intestinal injuries in dogs.
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Abstract
Endoscopic capsules and endoscopy were used to assess the speed of kill and the clearance of hookworms in dogs experimentally infected with Ancylostoma caninum. A total of four adult dogs were inoculated in two separate cohorts comprised of two 4-year-old females and two 7-year-old males. Dogs were treated topically with Advantage Multi(®) for Dogs 13 days (Cohort 1) or 16 days (Cohort 2) after infection. Endoscopic imaging of the small intestine was carried out both pre- and post-treatment. Examination of the first cohort revealed that the worms had been cleared and the hookworm-induced lacerations were markedly diminished within 48 h of treatment. In the second cohort, endoscopic capsules were given the day of, the day after, and two days after treatment; within 24h of product administration, the worms had been removed with a concurrent reduction in observed lesions. Topical application of Advantage Multi(®) for Dogs rapidly removed worms from the small intestine of the dogs in this study as early as 24h post-treatment, with a marked reduction in the number of mucosal lesions seen.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24953752/