Peer-reviewed veterinary case report
Retinal atrophy signs and testing in mixed breed dogs
By Balicki, Ireneusz et al.·Published in Acta veterinaria Hungarica·2024·1Department and Clinic of Animal Surgery·View original on PubMed →
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Original publication title: Assessment of retinal atrophy in mixed breed dogs using spectral domain optical coherence tomography (SD-OCT) and electroretinography.
- Species:
- dog
Plain-English summary
A group of mixed breed dogs with progressive retinal atrophy (a condition that leads to vision loss) underwent tests to assess their eye health. The dogs, aged between 1.5 and 14 years, showed varying degrees of retinal damage, with the most severe changes occurring near the optic nerve. Tests revealed that the retinal thickness was significantly reduced in these dogs compared to healthy ones, and most of the dogs had very low or unrecordable responses in their eye function tests. This study helps to understand how retinal atrophy affects vision in dogs and highlights the importance of using advanced imaging techniques for diagnosis.
People also search for: dog retinal atrophy symptoms · mixed breed dog vision loss · progressive retinal atrophy treatment
Abstract
The aim of the study was to characterize retinal atrophy (RA) with progressive retinal atrophy symptoms in mixed breed dogs using ophthalmoscopy, spectral domain optical coherence tomography (SD-OCT) and electroretinography (ERG).The study was performed on 13 mixed breed dogs affected by retinal atrophy (11 males and 2 females that were 1.5-14 years old). Depending on the advancement of RA, SD-OCT examinations identified retinal abnormalities ranging from layer disorganisation to advanced atrophy. The most advanced RA occurred ventral to the optic disc. Total retinal thickness in both eyes (mean ± SD) was lower in dogs with RA compared to controls dorsally (77.7 ± 39.5 μm vs 173.5 ± 13.3 μm), ventrally (33.4 ± 29.9 μm vs 139.5 ± 10.8 μm), nasally (65.0 ± 34.5 μm vs 163.9 ± 11.0 μm) and temporally (61.8 ± 41.7 μm vs 171.9 ± 11.1 μm) to the optic disc. In dogs with locally normal architecture of inner retina, loss of definition of outer retinal layers occurred in many regions. Dark and light-adapted ERGs were reduced in 2 dogs with RA and were unrecordable in 11 dogs. Lesions evident in SD-OCT scans of mixed breed dogs affected with retinal atrophy initially appear ventrally to the optic disc and ventro-dorsally in advanced RA. In all mixed breed dogs with retinal atrophy, clinical signs and SD-OCT results correlate with ERG findings.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38916958/