Peer-reviewed veterinary case report
Oral afoxolaner kills brown dog ticks on dogs for 35 days
By Kunkle, Bruce et al.·Published in Veterinary parasitology·2014·Merial Limited, United States·View original on PubMed →
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Original publication title: Assessment of the efficacy of orally administered afoxolaner against Rhipicephalus sanguineus sensu lato.
- Species:
- dog
Plain-English summary
A group of dogs was treated with a new oral medication called afoxolaner to get rid of ticks. The dogs had been infested with ticks before treatment, and the results showed that afoxolaner was highly effective, killing nearly all existing ticks within two days. Additionally, it continued to protect the dogs from new tick infestations for up to five weeks. This means that if your dog has a tick problem, afoxolaner could be a great option to consider for both immediate relief and long-term prevention.
People also search for: dog tick treatment · afoxolaner for dogs · how to get rid of ticks on dogs
Abstract
Two studies were conducted to confirm that a single oral dose of the novel insecticide/acaricide afoxolaner is efficacious against existing infestations of Rhipicephalus sanguineus sensu lato in dogs and can control re-infestation for up to 35 days. Each study utilized 16 purpose bred adult dogs using a controlled randomized block design. One or two days prior to treatment, all dogs were infested with 50 unfed adult ticks. On Day 0 one group was treated with an oral chewable formulation of afoxolaner at a dose as close as possible to the minimum dose of 2.5mg/kg. Weekly re-infestations with 50 adult unfed ticks were repeated for five weeks. Forty-eight hours after treatment and after each re-infestation, the number of remaining live ticks on each dog was counted. Treatment with afoxolaner resulted in efficacies of 98.8-100% within 48 h on existing tick infestations, while the efficacy against new tick infestations was >95.7% over five weeks.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24629425/