Peer-reviewed veterinary case report
How fast Frontline Tri-Act kills ticks on dogs
By Beugnet, Frédéric et al.·Published in Parasite (Paris, France)·2016·Merial SAS, France·View original on PubMed →
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Original publication title: Assessment of the prophylactic speed of kill of Frontline Tri-Act(®) against ticks (Ixodes ricinus and Rhipicephalus sanguineus) on dogs.
- Species:
- dog
Plain-English summary
A group of 16 healthy adult dogs was tested to see how quickly a topical treatment called Frontline Tri-Act worked against ticks. The dogs were exposed to two types of ticks, and those treated with Frontline Tri-Act showed over 90% effectiveness in killing the ticks just 6 hours after application. This effectiveness lasted for a full month, making it the first treatment to demonstrate such rapid and long-lasting protection against these ticks. Pet owners can feel reassured that this product can help keep their dogs safe from tick infestations.
People also search for: dog tick prevention · Frontline Tri-Act effectiveness · how fast does Frontline kill ticks
Abstract
The objective of the study was to assess the speed of kill of a single topical treatment with a combination of fipronil and permethrin (Frontline Tri-Act(®)/Frontect(®)) against experimental infestations of Ixodes ricinus and Rhipicephalus sanguineus ticks on dogs. In this parallel group designed, randomised, single centre, controlled efficacy study, 16 healthy adult dogs were allocated to two groups: 8 dogs were treated with the topical combination on Day 0 and the other 8 dogs served as untreated controls. Each dog was exposed in a crate to 100 I. ricinus (50 females, 50 males) and 50 R. sanguineus (25 males, 25 females) on Days 2, 7, 14, 21 and 28. Ticks were counted in situ at 6 and 12 h after exposure and removed at 24 h after exposure. Frontline Tri-Act(®) was effective (≥90%) against both R. sanguineus and I. ricinus tick infestations at 6, 12 and 24 h after exposure, from 2 to 28 days after treatment. This is the first time that a topical ectoparasiticide has demonstrated a preventive killing effect against these two tick species in 6 h for a full month.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26795064/