Peer-reviewed veterinary case report
ASSESSMENT OF THE REPRODUCTIVE TOXICITY OF THE DRUG INTERAMIN WITHIN THE FRAMEWORK OF PRECLINICAL TRIALS
- Journal:
- Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine
- Year:
- 2022
- Authors:
- Vostroilova, G.A. et al.
- Species:
- rodent
Abstract
The article describes the results of an experimental study of the embryotoxic and teratogenic effects of the new combination drug interamin. The analysis of the data obtained indicates the absence of any negative effect on female white rats during the entire pregnancy when administered at the studied doses (0.1 ml/kg and 1.0 ml/kg), absence of induction of pre- and post-implantation death, total embryonic mortality, pathologies of organogenesis and development of the fetal skeletal system, disorders of postnatal development of newborn animals. Based on this, no signs of embryotoxic and teratogenic effects of interamin were detected.
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Search related cases →Original publication: https://doi.org/10.52368/2078-0109-2022-58-3-18-21