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Peer-reviewed veterinary case report

Dust buildup in dog lungs linked to lung cancer risk

By Bettini, Giuliano et al.·Published in Veterinary journal (London, England : 1997)·2010·Department of Veterinary Public Health and Animal Pathology, Italy·View original on PubMed

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Original publication title: Association between environmental dust exposure and lung cancer in dogs.

Species:
dog

Plain-English summary

A study found that dogs exposed to high levels of black dust in their lungs had an increased risk of developing lung cancer. Researchers looked at 35 dogs with lung cancer and compared them to 160 healthy dogs. They discovered that the most common type of lung cancer was papillary adenocarcinoma, often diagnosed at an early stage. The findings suggest that inhaling polluted air may be linked to a higher chance of lung cancer in dogs.

People also search for: dog lung cancer symptoms · black dust in dog lungs · lung cancer treatment for dogs · why is my dog coughing · signs of lung cancer in dogs

Abstract

The objective of this study was to investigate the relationship between the accumulation of black dust matter in lungs (anthracosis) and primary lung cancer in dogs. A retrospective study was carried out on material from 35 dogs with primary lung cancer and 160 controls. The amount, histological appearance and birefringence of anthracosis were assessed in pulmonary specimens by light microscopy, and the odds ratio (OR) calculated for dogs with primary lung cancer. The same factors were analysed to identify an association between tumour histotype, histological grade, and clinical stage. Papillary adenocarcinoma was most commonly diagnosed (45.7%). The majority of tumours were of histological grade II, and the lung cancer was more often localised (clinical stage I). An increased risk of lung cancer was observed in dogs with higher amounts of anthracosis (OR: 2.11, CI 95%: 1.20-3.70; P < 0.01), which suggests an association between anthracosis due to inhalation of polluted air and lung cancer in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20044284/