Peer-reviewed veterinary case report
High triglycerides linked to pancreatic enzyme levels in miniature
By Xenoulis, Panagiotis G et al.·Published in Journal of the American Animal Hospital Association·2010·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Association between serum triglyceride and canine pancreatic lipase immunoreactivity concentrations in miniature schnauzers.
- Species:
- dog
Plain-English summary
A group of 195 miniature schnauzers was studied to see if high levels of fat in the blood (hypertriglyceridemia) were linked to increased levels of a specific enzyme (cPLI) that indicates pancreatitis. The results showed that schnauzers with high triglycerides were much more likely to have elevated cPLI levels, suggesting a higher risk of pancreatitis. Specifically, those with triglyceride levels above 862 mg/dL were 4.5 times more likely to show signs of pancreatitis. This information can help pet owners understand the importance of monitoring their schnauzer's blood fat levels to prevent potential health issues.
People also search for: miniature schnauzer pancreatitis symptoms · high triglycerides in dogs · dog cPLI test results
Abstract
The objective of this study was to investigate possible associations between serum triglyceride and canine pancreatic lipase immunoreactivity (cPLI) concentrations in miniature schnauzers. One hundred and ninety-five miniature schnauzers were enrolled and divided into two groups based on whether they had normal (group 1) or increased (group 2) serum triglyceride concentrations. Serum cPLI concentrations were measured and compared between groups. A significant positive correlation was seen between serum triglyceride and cPLI concentrations (Spearman r=0.321; P<0.0001). Miniature schnauzers with hypertriglyceridemia had a significantly higher median serum cPLI concentration (99.5 microg/L) than miniature schnauzers with normal serum triglyceride concentrations (median cPLI concentration 39.3 microg/L; P=0.0001). A cutoff value of 862 mg/dL was selected for serum triglyceride concentrations based on receiver operator characteristic analysis. Miniature schnauzers with severe hypertriglyceridemia (> or =862 mg/dL) were 4.5 times more likely to have a serum cPLI concentration consistent with pancreatitis (> or =200 microg/L) than miniature schnauzers with a normal serum triglyceride concentration. The present study supports an association between hypertriglyceridemia (especially when severe [> or =862 mg/dL]) and high cPLI concentrations in miniature schnauzers.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20610694/