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Peer-reviewed veterinary case report

MRI syringomyelia signs predict later symptoms in Cavalier King

By Ives, E J et al.Ā·Published in Veterinary journal (London, England : 1997)Ā·2015Ā·The Queen's Veterinary School Hospital, United KingdomĀ·View original on PubMed →

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Original publication title: Association between the findings on magnetic resonance imaging screening for syringomyelia in asymptomatic Cavalier King Charles spaniels and observation of clinical signs consistent with syringomyelia in later life.

Species:
dog

Plain-English summary

A group of 79 Cavalier King Charles Spaniels that showed no symptoms were screened with MRI for a condition called syringomyelia (SM), which can cause serious issues later in life. Owners later reported that 13 of these dogs developed signs of SM, with a higher percentage of those having a syrinx (a fluid-filled cavity) visible on the MRI. Specifically, 36% of dogs with a syrinx showed symptoms later, compared to only 7% of those without one. This suggests that MRI findings could help predict which dogs might develop problems in the future, but more research is needed to confirm this.

People also search for: Cavalier King Charles Spaniel syringomyelia symptoms Ā· MRI for dog syringomyelia Ā· how to treat syringomyelia in dogs

Abstract

A questionnaire-based study was used to investigate the association between the findings on magnetic resonance imaging (MRI) screening for syringomyelia (SM) in 79 asymptomatic Cavalier King Charles spaniels (CKCS) and the subsequent development of clinical signs consistent with SM in later life. Owners reported clinical signs consistent with SM in 13/79 (16%) dogs at the time of the questionnaire. A significantly greater proportion of CKCS with a syrinx visible on MRI screening showed clinical signs in later life (9/25, 36%) than dogs without a visible syrinx (4/54, 7%; odds ratio 6.9). Whether the findings of MRI screening can be used to indicate the likelihood of an asymptomatic CKCS developing clinical signs consistent with SM in later life warrants further prospective study in a larger cohort of dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25475164/