Peer-reviewed veterinary case report
Pulmonary artery flow and right heart changes in dogs with pulmonic
By Duble, E H et al.·Published in Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2026·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Association of pulmonary arterial end-diastolic forward flow and right heart remodeling in dogs with congenital pulmonic stenosis and precapillary pulmonary hypertension.
- Species:
- dog
Plain-English summary
A group of dogs with congenital heart issues, specifically pulmonic stenosis (a narrowing of the heart valve) and precapillary pulmonary hypertension (high blood pressure in the lungs), showed higher blood flow measurements in their main pulmonary artery compared to healthy dogs. This increased blood flow was linked to changes in the structure of the right side of their hearts, indicating that these dogs had more severe heart problems. The findings suggest that monitoring this blood flow could help veterinarians assess the severity of heart disease in affected dogs. Treatment options would depend on the specific condition and severity, but early detection is key for better management.
People also search for: dog heart problems pulmonic stenosis · symptoms of pulmonary hypertension in dogs · treatment for dog heart disease
Abstract
INTRODUCTION/OBJECTIVES: Main pulmonary artery end-diastolic forward flow (EDFF) has been evaluated as an indicator of right ventricular (RV) restrictive physiology (RVRP) in humans. The authors theorized that dogs with conditions associated with RVRP, including pulmonic stenosis (PS) and precapillary pulmonary hypertension (PH), would have an increased EDFF magnitude compared to normal dogs and that EDFF velocity in dogs with PS or PH would be correlated with disease severity and RV remodeling. ANIMALS, MATERIALS AND METHODS: Echocardiographic studies of client-owned dogs, including 50 each with PS or PH and 12 without heart disease, were retrospectively reviewed to obtain maximum EDFF velocity and right heart structural measurements. Differences between EDFF velocities in dogs with PS or PH and dogs in their respective age- and weight-matched control groups were assessed using Mann-Whitney U non-parametric tests. Spearman's rho non-parametric correlations were evaluated between EDFF velocity, right heart structural measurements, and PS and PH severity indices. RESULTS: Maximum EDFF velocity was significantly higher in dogs with PS (P<0.001) or PH (P=0.018) than in controls. In PS dogs, EDFF velocity was positively correlated with RV free wall thickness (P=0.047) and pulmonic valve peak pressure gradient (P=0.007). STUDY LIMITATIONS: Retrospective study design impacted case selection and echocardiographic measurement accuracy. CONCLUSIONS: The results of this study support the presence of RVRP in dogs with PS and PH. The contrasting associations of EDFF and RV dimensions with PS severity versus PH highlight differences in RV remodeling between these diseases.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41456363/