Peer-reviewed veterinary case report
Urinary cadmium linked to high blood pressure in senior cats
By Finch, N C et al.·Published in The Veterinary record·2012·School of Veterinary Sciences, United Kingdom·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Association of urinary cadmium excretion with feline hypertension.
- Species:
- cat
Plain-English summary
A group of senior cats, some with high blood pressure (hypertension) and some with normal blood pressure, were studied to see if there was a link between urinary cadmium levels and hypertension. The researchers found that cats with high blood pressure had higher levels of cadmium in their urine compared to those with normal blood pressure. This suggests that exposure to cadmium might contribute to developing high blood pressure in cats. If your cat is older and has been diagnosed with hypertension, it may be worth discussing potential environmental exposures with your veterinarian.
People also search for: cat high blood pressure causes · senior cat hypertension treatment · cadmium exposure in cats
Abstract
Fifty client-owned senior cats (32 normotensive and 18 hypertensive) with renal function ranging from normal to moderately reduced were recruited into a prospective cross-sectional study exploring the association of urinary cadmium excretion and hypertension in cats. Heparinised plasma samples were collected and analysed for routine biochemical parameters. Urine samples were collected via cystocentesis and were analysed for cadmium concentrations using inductively coupled plasma mass spectrometry (ICP-MS). Blood pressure was measured using the Doppler method. Urinary cadmium concentrations were indexed to urinary creatinineconcentration. Comparison of urinary cadmium excretion was made between hypertensive and normotensive cats.The median (range) urinary cadmium concentration standardised to urinary creatinine concentration (UCdCr) in the normotensive and hypertensive cats was 0.08 (0.02 to 0.37) and 0.12 (0.02 to 1.38) nmol/mmol creatinine. The UCdCr was significantly higher in hypertensive compared with normotensive cats (P=0.016). UCdCr and plasma creatinine concentration remained independent predictors of hypertensive status in a logistic regression model. UCdCr and plasma creatinine concentration were not correlated (r=-0.01, P=0.956). These data suggest cadmium exposure and accumulation in cats may play a role in the development of feline hypertension.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22141113/