Peer-reviewed veterinary case report
Ataxin-2 Is Droppin' Some Knowledge.
- Journal:
- Neuron
- Year:
- 2018
- Authors:
- Becker, Lindsay A & Gitler, Aaron D
- Affiliation:
- Department of Genetics · United States
Abstract
Ataxin-2 is an RNA-binding protein involved in translation regulation and mutated in neurodegenerative diseases, including ALS. In this issue of Neuron, Bakthavachalu et al. (2018) demonstrate that higher-order ataxin-2 RNA/protein assemblies are necessary for both translation-dependent learning and ALS-associated neurodegeneration in Drosophila.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29772196/